BL-UP Basic Langendorff Isolated Heart Systems on UP-100 base
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- Turnkey system for perfusing isolated rodent hearts in Langendorff
mode, includes perfusion system, transducers, amplifiers, data
acquisition
- Perfusion is carried out under Constant pressure condition
- Ideal replacement for perfusion system with hydrostatic pressure
generation, low perfusate volume in use, perfusion pressure up
to 300 mmHg possible
- Can be equipped with oxygenator for optimal aeration of perfusate
containing albumin or erythrocytes
- Easy and compact
- Application
- If isolated heart is only used occasionally or for limited
tests
- For student lab
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Specifications
Operating Modes:
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Version LH |
Only Langendorff Mode at constant pressure or constant flow |
Limiting Data:
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Aorta |
ID 0.8 to 2.5 mm |
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Perfusion Flow |
Up to 25 ml/min |
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Perfusion Pressure |
Up to 300 mmHg |
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The basic Langendorff Isolated Heart System BL-UP is a ready
to use isolated heart perfusion system for rodent hearts such
as mouse, rat and guinea pig. This system is based on our more
advanced UP-100 isolated heart system for constant flow or pressure
perfusion. To achieve constant constant pressure perfusion, the
BL-UP utilizes our SCP Controller module. The SCP module in combination
with a pressure transducer an amplifier and the peristaltic pump
controls the perfusion pressure. The complete system includes
the perfusion apparatus, the transducers and amplifiers for perfusion
pressure, the servo controller and integrated peristaltic pump,
the isovolumetric left ventricular pressure measurement (isovolumetric
balloon method) using a second pressure transducer and amplifier
and a data acquisition system. The BL-UP is optimized and intended
only for Langendorff heart perfusion. The system is simple to
setup and use and is available for mouse, rat, and/or guinea pig
hearts.
The use of the SCP module allows continuous recording of flow
rate without an expensive flowmeter.
The following signals are recorded:
- Isovolumetric left ventricular pressure (Balloon)
- dLVP/dt
- Perfusion pressure
- Perfusion flow
The software evaluates the following parameters:
- Systolic and diastolic LVP
- Heart rate
- dP/dt max, dP/dt min, Contractility index
- Mean perfusion pressure
- Mean perfusion flow
- Coronary resistance
HUGO SACHS ELEKTRONIK-HARVARD
APPARATUS GmbH
Gruenstrasse 1 · D-79232 March-Hugstetten · GERMANY
Phone: +49 (0) 76 65 - 92 00-0 · Fax: +49 (0) 76 65 - 92
00-90
