Graz Tissue Bath System
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- Designed for vascular rings but suitable for most standard
pharmacological experiments
- Permits experiments both on smooth muscle, cardiac (atria),
or skeletal muscles preparations
- Clear, 4-channel arrangement
- Rigid construction
- Contractions can be measured isometrically or isotonically
- Interchangeable tissue vessels: 2, 5, 10 or 20 ml
- Experiments with minimum test substance quantities are possible
using small tissue vessels
- Adaptable to different tissue preparations by suitable form
of tissue supports
- Tissue holders with integral field stimulating electrode
available
- Simple to operate, easy to clean
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The Graz Organ Bath can be used for many standard pharmacological
experiments.
This apparatus was developed for experiments on small isolated
vascular rings (1 to 2 mm dia.) with special attention to
a low incubation volume of the medium. The smallest tissue vessel
available has a volume of 2 ml. The muscle contractions
produced in these experiments can be measured either as forces
(isometrically) or as displacements (isotonically). The organ
bath is also available in variable versions. Larger tissue vessels
of 5, 10 or 20 ml are available for larger vessels and
other muscle preparations.
These baths can also be used for experiments on papillary
muscle or isolated atria (e.g. guinea-pig), with provision
for electrical stimulation.
The F-30 isometric transducer that we recommend can easily
be replaced by different transducers without any modification
of the apparatus.
The main consideration in designing the bath has been a simple
and clear arrangement, without neglecting the necessary stability.
A rigid construction is an essential requirement for measuring
small contraction forces. A rigid Plexiglas baseplate carriers
4 vertical rods on which the individual components are mounted.
Tissue vessels and suitable holders are available in 4 different
sizes. The perfusion solution is aerated by glass frits fused
into the vessel bottom. A needle valves is provided for each tissue
vessel to permit accurate adjustment of the gas flow.
Checklist for more information
or quotation on
Isolated Tissue Systems
HUGO SACHS ELEKTRONIK-HARVARD
APPARATUS GmbH
Gruenstrasse 1 · D-79232 March-Hugstetten · GERMANY
Phone: +49 (0) 76 65 - 92 00-0 · Fax: +49 (0) 76 65 - 92
00-90