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For the perfusion of the isolated heart according to Langendorff,
the universal perfusion system UP-100 can be equipped with a jacketed
heart chamber and the additional measurement system for isovolumetric
LVP using a latex balloon with spindle syringe for diastolic pressure
adjustment. The setup represents a compact unit. It can be used
for constant pressure or constant flow perfusion of isolated hearts
of mice, guinea pigs, rats and small rabbits as long as the coronary
flow is below 100 ml/min.
The heart is connected via the aortic cannula to the heat exchanger
which acts also as bubble trap. The equipment for measurement
of coronary flow or for electrogram can also be adapted. If perfusate
containing albumin or erythrocytes is used, the oxygenation can
be optimized with the additional bulb oxygenator.
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HUGO SACHS ELEKTRONIK-HARVARD
APPARATUS GmbH
Gruenstrasse 1 · D-79232 March-Hugstetten · GERMANY
Phone: +49 (0) 76 65 - 92 00-0 · Fax: +49 (0) 76 65 - 92
00-90