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Metabolic Chamber for Mouse

SKU
ebdbd903

The Metabolic Chamber for Mouse is designed to house individual mice for 24-hour periods or longer for the purpose of studying the animal’s metabolic function or effects of intervention on the animal’s metabolism.

  • Designed specifically to house individual mice
  • Conforms to code for isolator units
  • Constructed from high impact resistance acrylic
  • Lid holds disposable air filter pad
  • All connections sealed with O-rings
  • Removable, disposable urine vessel
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The Metabolic Chamber for Mouse is designed to house individual mice for 24-hour periods or longer for the purpose of studying the animal's metabolic function or effects of intervention on the animal's metabolism. These include, but are not limited to, daily food and water intake, effects of different drug therapies, urinary protein excretion and renal function studies. This chamber is specifically designed to accurately separate urine from feces for analysis. The chamber is an isolator unit that conforms to the housing specifications in the Guide for the Care and Use of Laboratory Animals.

  • Designed specifically to house individual mice
  • Conforms to code for isolator units
  • Constructed from high impact resistance acrylic
  • Lid holds disposable air filter pad
  • All connections sealed with O-rings
  • Removable, disposable urine vessel

The chamber is constructed of gas sterilizable acrylic and all connections are sealed with O-rings. The lid holds a disposable air filter pad. The urine/feces separation cone is stainless steel, as are the floor and filter screens. The urine collection vessel is removable and disposable. The chamber is therefore suitable for use in barrier facilities. These chambers are actively used in research projects which have been reported in presentations at national scientific meetings. The chambers have proven to be particularly useful for research involving transgenic mice which must be housed individually for phenotyping and metabolic studies.

Note: These publications reference a “specially constructed” metabolic cage. This cage is the Metabolic Chamber for Mice.

1. Flemming ER, Athirakul K, Oliverio MI, Key M, Goulet J, Koller BH, Coffman TM. Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2. Am J Physiol 1998; 275:F955-61.
2. Oliverio MI, Delnomdedieu M, Best CF, Li P, Morris M, Callahan MF, Johnson GA, Smithies O, Coffman TM. Abnormal water metabolism in mice lacking the type 1A receptor for angiotensin II. Am J Physiol (Renal Physiology) 2000; 278:F75-82.
3. Oliverio MI, Best CF, Smithies O, Coffman TM. Regulation of sodium balance and blood pressure by the AT1A receptor for angiotensin II. Hypertension 2000; 35:550-4.
4. Pace AJ, Lee E, Athirakul K, Coffman TM, O’Brien DA, Koller BH. Failure of spermatogenesis in mouse lines deficient in the Na+-K+-2Cl- cotransporter. J Clin Invest 2000; 105:441-50.
5. Athirakul K, Kim H-S, Audoly LP, Smithies O, Coffman TM. Deficiency of COX-1 causes natriuresis and enhanced sensitivity to ACE inhibition. In Press, Kidney Int.

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