UP-100IH Core Systems

The UP-100IH is a universal perfusion system adapted for basic Langendorff perfusion studies primarily in rat, guinea pig and juvenile rabbit heart. It can be used for mouse heart as well. It is the preferred system for simple compound screening that requires basic measured parameters such as aortic pressure, left ventricular pressure (isovolumetric LVP) and ECG Lead II measurement.

There are two UP-100IH Core Systems to choose from. These complete systems include all the primary equipment you need to accomplish the basic Langendorff experiment, only requiring the addition of species specific cannulae.

The UP-100IH Basic Core System is the more common configuration. It allows you to measure aortic pressure and left ventricular pressure (LVP), as well as two to three additional parameters of your choice.  Most researchers will also want to operate in a constant pressure perfusion mode and measure coronary flow, which is a simple addition to the basic system.

The UP-100IH Advanced Core System allows up to the full range of available measured parameters beyond the aortic pressure and left ventricular pressure (LVP) that are included in the Basic Core System. Measurements such as direct coronary flow, ECG lead II, temperature and metabolic parameters (pH, pO2, pCO2) can easily be added.

To ensure that your system is properly configured as a functional unit that meets your application needs, please complete our Checklist and contact Technical Services before placing an order. In Europe, please call +49 7665-9200-0 or email sales@hugo-sachs.de. For other regions, call 800-547-6766 or email support@hbiosci.com.

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