Addiction is a state in which an organism engaged in a compulsive behavior which is reinforced or rewarded, even when faced with negative consequences.

Given that drug abuse is a major public health problem calling new therapeutic strategies, animal models have been developed in order to study behavioral and neurobiological basis of addiction. Actual rodent models have predictive validity and are reliable for the study of the addictive potential of substances, the mechanisms underlying the transition from drug use to addiction and the relapse or the individual vulnerability phenomenon.

Learn more about the study of reward and addiction.

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